Lyophilization, or freeze-drying, enables room-temperature storage and transport of temperature-sensitive reagents and assays. Beyond improving shelf life and stability, lyophilized products offer enhanced usability in point-of-care, point-of-use, and field-based settings. Whether you're looking for off-the-shelf lyophilized products, reagents optimized for lyophilization, or custom lyophilization of your own formulation, NEB is here to support your workflow.

NEB has over 50 years of experience in enzyme formulation and extensive expertise in lyophilization; we offer flexible, science-driven lyophilization solutions tailored to your specific goals. Our team has developed and optimized freeze-dried reagents across a wide range of applications, ensuring consistent performance, stability, and ease of use. By combining formulation know-how with lyophilization expertise, NEB offers streamlined, end-to-end solutions from development to delivery backed by the quality and reliability you trust.

Explore our Solutions

  1. Ready-to-Use Lyophilized Products: We have optimized excipients and drying conditions to ensure our lyophilized products deliver high performance and stability. These ready-to-use formats not only simplify and streamline your workflow, but they also offer a foundation on which you can customize to meet your specific assay needs.
    Product Name Application
    LyoPrime Luna® Probe One-Step RT-qPCR Mix with UDG  RT-qPCR
    LyoPrime WarmStart Fluorescent LAMP/RT-LAMP Mix (with UDG) LAMP & RT-LAMP with fluorescent detection
    LyoPrime WarmStart LAMP/RT-LAMP Mix (with UDG) 

    (Available through Customized Solutions: contact us to order)
    LAMP & RT-LAMP with alternative detection methods 
    Monarch® DNase I, Lyophilized   Nucleic Acid Purification, Cloning, Synthetic Biology

     

  2. Glycerol-free & Lyo-compatible Reagents: NEB offers a broad selection of reagents in glycerol-free and lyo-compatible formulations to support your lyophilization needs. View some of our most popular products below or access the complete list.
    Product Name Recommended Application
    Bst-XT WarmStart™ DNA Polymerase (Glycerol-free)   LAMP
    Bst 2.0 WarmStart® DNA Polymerase (Glycerol-free)   LAMP
    WarmStart® RTx Reverse Transcriptase (Glycerol-free)   RT-LAMP 

     

  3. Custom Lyophilization: When you engage with us for custom lyophilization, we take the time to understand your intended use, workflow, and project objectives. This informs how we approach your formulation and helps guide decisions around format and packaging. Whether you're building on an existing NEB lyophilized product (adding primers or making small adjustments) or developing a completely bespoke formulation, our team is here to support you.

    As both the developer and manufacturer of our enzymes, we have unique visibility into formulation and production details, along with direct access to reagents, effectively simplifying supply chain logistics. We also often work with third-party reagents and can source materials from your preferred suppliers.

 

Lyophilization formats 3-up – scale plate and cake

 

Contact us to learn more 
or discuss your project
 

 

Products and content are covered by one or more patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc (NEB). The use of trademark symbols does not necessarily indicate that the name is trademarked in the country where it is being read; it indicates where the content was originally developed. All other trademarks are the property of their respective owners. The use of this product may require the buyer to obtain additional third-party intellectual property rights for certain applications. For more information, please email busdev@neb.com.

 

 

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Find out how NEB Lyophilization Sciences can support the development of your custom lyophilized assay.

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