A letter from NEB's CEO

Dear Researcher,

For over 50 years, NEB has prioritized the advancement of science in everything we do. We recognize the role science plays in improving
human health, in understanding the world around us, and in preserving that world for future generations.

We also recognize the uncertainties many of us in the life sciences are facing today. These uncertainties stem from concerns about the
impact of tariffs, the real potential for reductions in US government funding for science, and a variety of other factors. For many of you,
this has already disrupted the important science you are doing. Unfortunately, unless corrected or minimized quickly, these issues are
likely to have long-lasting impacts on life science innovation that are difficult to fully appreciate in the short term.

While surcharges and tariffs may increase NEB’s costs, we will not pass these additional increases on to customers. We prefer you use
your funding to advance science. Further, nearly all NEB’s products are manufactured in the US and we have a robust supply chain
that minimizes the impact of any raw materials sourced internationally. We will continue to do everything we can to get you the critical
reagents you need.

If you have questions, or if there is anything you feel we should be doing differently to support your research, reach out. By working
together, we can continue to shape the science of tomorrow.

Thank you and wishing you success in your research,

Sal Russello
Chief Executive Officer
New England Biolabs, Inc.